How Does CBD And THC Work Together?


Cannabidiol (CBD), the cannabinoid popular for its potential therapeutic effects is one of more than a hundred cannabinoids found in the cannabis family of plants. Tetrahydrocannabinol (THC) is another well-known cannabinoid known for its psychotropic effects. These cannabinoids have structure and function like the endocannabinoids produced by our bodies. In this article, we will investigate how CBD and THC work together.


THC and CBD are the two important cannabinoids found in hemp plant extracts People consume them separately or together for mitigating the symptoms of various ailments as well as for recreational purposes. Both are isomers, i.e. they have the same molecular formula but different molecular structures. This is the reason, CBD is non-psychotropic, while THC is psychotropic.

The Entourage Effect

Some research suggests that a combination of these cannabinoids can be more effective for treating conditions like chronic pain. It is believed that this enhancement in their effects is due to the entourage effect. This happens when the cannabinoids, aromatic compounds called terpenes, flavonoids, and other phytochemicals work together to enhance their effect, and this phenomenon is called the entourage effect. Furthermore, full-spectrum cannabidiol (CBD) products are more popular among consumers due to this effect.

What Does The Research Say About Taking THC And CBD Together?

Additional Therapeutic Benefits: Consuming THC and CBD along with terpenes can be beneficial for the following conditions:

  • Anxiety
  • Pain
  • Inflammation
  • Epilepsy

To Reduce Unwanted Effects Of THC: In some people, THC can produce unwanted effects like sedation, anxiety, paranoia, and increased hunger. This can be reduced when CBD is consumed along with it. You must know that cannabidiol reduces the affinity of ECS receptors that bind with tetrahydrocannabinol.

Brain Health: A combination of THC and CBD provides neuroprotection and has anti-inflammatory effects. Studies show that this combination can be useful for reducing the severity of symptoms in neurodegenerative diseases like Parkinson’s. For example, it improves their mobility by reducing tremors.

The Best THC And CBD Ratio

Beginners can start with a CBD to THC ratio of 1:1, i.e. 5 mg of cannabidiol and 5 mg of tetrahydrocannabinol. Once you get used to it, you can gradually increase the quantity of CBD.

On a final note, before taking THC and CBD together, it is important to consult with your physician. Also, keep in mind that these cannabinoids cannot cure ailments.